Material Safety Data Sheet
2,4-Pentanedione, 99+%
ACC# 00031
Section 1 - Chemical Product and Company Identification |
MSDS Name: 2,4-Pentanedione, 99+%
Catalog Numbers:
AC129960000, AC129960010, AC129960050, AC129965000
Synonyms:
2,4-Pentanedione; Acetylacetone.
Company Identification:
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North America, call: 800-ACROS-01
For emergencies in the US, call CHEMTREC: 800-424-9300
Section 2 - Composition, Information on Ingredients
|
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
123-54-6 | 2,4-Pentanedione |
>99 | 204-634-0 |
Hazard Symbols: XN
Risk Phrases: 10 22
Section 3 - Hazards Identification
|
EMERGENCY OVERVIEW
Appearance: colorless or slight yellow liquid. Flash Point: 34 deg C.
Warning! Flammable liquid and
vapor. May cause central nervous system depression.
Harmful if swallowed or absorbed through the skin. Causes eye and
skin irritation. Causes respiratory tract irritation. May cause
fetal effects based upon animal studies.
Target Organs: Central nervous system.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis and
corneal damage.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Chronic exposure may cause chelation with iron and other soluble
metals leading to deficiencies. Exposure to low concentrations may
be cumulative. May cause irritation and dermatitis. May cause
cyanosis of the extremities.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. May cause effects similar to those for inhalation exposure.
Ingestion of large amounts may cause CNS depression.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. May cause respiratory tract irritation. Aspiration may lead
to pulmonary edema. Vapors may cause dizziness or suffocation. May
cause burning sensation in the chest.
Chronic:
Animal studies have reported that fetal effects/abnormalities may
occur when maternal toxicity is seen. Chronic exposure may cause
chelation with iron and other soluble metals leading to deficiencies.
Exposure to low concentrations may be cumulative. Laboratory
experiments have resulted in mutagenic effects.
Section 4 - First Aid Measures
|
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes.
Ingestion:
Call a poison control center. If swallowed, do not induce vomiting
unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
|
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Will burn
if involved in a fire. Use water spray to keep fire-exposed
containers cool. Containers may explode in the heat of a fire.
Flammable liquid and vapor.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. For large fires, use water spray, fog, or
alcohol-resistant foam. Use water spray to cool fire-exposed
containers. Water may be ineffective. Do NOT use straight streams of
water.
Flash Point: 34 deg C ( 93.20 deg F)
Autoignition Temperature: 644 deg F ( 340.00 deg C)
Explosion Limits, Lower:Not available.
Upper: Not available.
NFPA Rating:
(estimated) Health: 2; Flammability: 2; Instability: 0
Section 6 - Accidental Release Measures
|
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Provide ventilation. A vapor suppressing
foam may be used to reduce vapors.
Section 7 - Handling and Storage
|
Handling:
Use only in a well-ventilated area. Ground and bond containers when
transferring material. Use spark-proof tools and explosion proof
equipment. Do not get in eyes, on skin, or on clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Keep container tightly closed. Avoid contact with heat,
sparks and flame. Do not ingest or inhale. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to
heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
Flammables-area.
Section 8 - Exposure Controls, Personal Protection
|
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA - Final PELs |
2,4-Pentanedione | none listed |
none listed | none listed |
OSHA Vacated PELs:
2,4-Pentanedione:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
Section 9 - Physical and Chemical Properties
|
Physical State: Liquid
Appearance: colorless or slight yellow
Odor: putrid odor
pH: Not available.
Vapor Pressure: 6 mm Hg @ 20 deg C
Vapor Density: 3.5 (Air=1)
Evaporation Rate:0.75 (n-butyl acetate=1)
Viscosity: Not available.
Boiling Point: 139-141 deg C
Freezing/Melting Point:-23 deg C
Decomposition Temperature:Not available.
Solubility: Soluble.
Specific Gravity/Density:0.973
Molecular Formula:C5H8O2
Molecular Weight:100.12
Section 10 - Stability and Reactivity
|
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, light, ignition sources, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents, strong reducing agents, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon
dioxide.
Hazardous Polymerization: Has not been reported.
Section 11 - Toxicological Information
|
RTECS#:
CAS# 123-54-6: SA1925000
LD50/LC50:
CAS# 123-54-6:
Draize test, rabbit, eye: 20 mg Severe;
Oral,
mouse: LD50 = 951 mg/kg;
Oral, rat: LD50 = 55 mg/kg;
Skin,
rabbit: LD50 = 810 uL/kg;
Carcinogenicity:
CAS# 123-54-6:
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology:
No information available.
Teratogenicity:
Inhalation, rat: TCLo = 398 ppm/6H (female 6-15 day(s) after
conception) Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus).
Reproductive Effects:
No information available.
Neurotoxicity:
No information available.
Mutagenicity:
Dominant Lethal Test: Inhalation, rat = 694 ppm/6h/5D.; Mutation in
Mammalian Somatic Cells: Hamster, Ovary = 80 mg/L.
Other Studies:
No information available.
Section 12 - Ecological Information
|
Ecotoxicity:
No data available.
released to soil, acetyl acetone is expected to leach readily
(estimated Koc range of 6 to 28) and volatilize from dry soil
surfaces. One screening study suggests that biodegradation may be the
predominant fate process in water. Although this study is not
specific to soil media, it suggests that biodegradation in soil may
be important. If released to water, hydrolysis, aquatic oxidation,
adsorption to sediment and bioconcentration in aquatic organisms are
not expected to be environmentally important removal processes of
acetylacetone.
Environmental:
Volatilization half-lives of 15 and 170 days have been estimated for
a model river (one meter deep) and a model environmental pond,
respectively. If released to the atmosphere, acetyl acetone is
expected to exist in the vapor phase. Vapor-phase acetyl acetone is
expected to degrade by reaction with photochemically produced
hydroxyl radicals (estimated half-life of 14 days). Based on its
high water solubility, removal from air via wet deposition may occur.
Physical:
No information available.
Other:
No information available.
Section 13 - Disposal Considerations
|
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
|
|
US DOT |
IATA |
RID/ADR |
IMO |
Canada TDG |
Shipping Name: |
PENTANE-2,4-DIONE |
|
|
|
No information available. |
Hazard Class: |
3 |
|
|
|
|
UN Number: |
UN2310 |
|
|
|
|
Packing Group: |
III |
|
|
|
|
Section 15 - Regulatory Information
|
US FEDERAL
TSCA
CAS# 123-54-6 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
CAS# 123-54-6: 5a2/12b
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 123-54-6: acute, chronic, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
STATE
CAS# 123-54-6 can be found on the following state right to know
lists: New Jersey, Pennsylvania, Massachusetts.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 10 Flammable.
R 22 Harmful if swallowed.
Safety Phrases:
S 21 When using do not smoke.
S 23 Do not inhale gas/fumes/vapour/spray.
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 123-54-6: 1
Canada - DSL/NDSL
CAS# 123-54-6 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D1B, D2B.
Canadian Ingredient Disclosure List
CAS# 123-54-6 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
Section 16 - Additional Information
|
MSDS Creation Date: 6/25/1999
Revision #3 Date: 12/03/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.